Dr. Thomas John Rosol

COS Expertise®

Ohio State University

Office of Research

Special Assistant to the Senior Vice President for Technology Licensing & CommercializationAppointed: 2008

Ohio State University

College of Biological Sciences

Molecular Genetics

Molecular Genetics Graduate Program

Graduate School FacultyAppointed: 2002

Ohio State University

College of Medicine

Surgery

Urology

Adjunct ProfessorAppointed: 2001

Ohio State University

College of Veterinary Medicine

Veterinary Clinical Sciences

Research

Graduate School FacultyAppointed: 1999

Ohio State University

College of Veterinary Medicine

Veterinary Biosciences (Veterinary Pathobiology)

ProfessorAppointed: 1996

Ohio State University

College of Dentistry

Oral Biology

Research

Graduate School FacultyAppointed: 1992

Ohio State University

College of Veterinary Medicine

Veterinary Biosciences

Research

Graduate School FacultyAppointed: 1992

Ohio State University

Office of Health Sciences

Comprehensive Cancer Center

Full MemberAppointed: 1987

Mailing Address

Ohio Sate University

1925 Coffey Road

Columbus, Ohio 43210

United States

Contact Information

Phone: (614) 292-5661

Fax: (614) 292-6473

Mobile: (614) 668-0513

rosol.1@osu.edu

http://www.vet.ohio-state.edu/ThomasRosol.htm

Qualifications

Diplomate, American College of Veterinary Pathologists, Anatomic Veterinary Pathology, 1987.

Ph.D., Ohio State University, Experimental Pathobiology, 1986.

D.V.M., University of Illinois, Veterinary Medicine (Valedictorian, 1st of 86 Students), 1981.

B.S., University of Illinois, Veterinary Medicine (Highest Honors), 1979.

B.S., University of Illinois, Agricultural Science (Highest Honors), 1978.

Expertise and Research Interests

Thomas J. Rosol, DVM, PhD served as the Dean of the College of Veterinary Medicine (2005-2008) and currently serves as a Special Assistant to the Senior Vice President for Research for Technology Licensing and Commercialization. He is a Professor of Veterinary Pathobiology in the Department of Veterinary Biosciences in the OSU College of Veterinary Medicine.

Dr. Rosol maintains an active, NIH-funded research laboratory that uses molecular, in vitro, and in vivo techniques to investigate the pathogenesis of human and animal cancers. Specifically, the laboratory develops mouse models of cancer to study the pathogenesis of bone metastasis, cancer-associated hypercalcemia, and human HTLV-1-induced T-cell lymphoma. The molecular regulation of parathyroid hormone-related protein is studied in vitro and in vivo using animal models of prostate, lung, and breast cancer, and lymphoma. Breast and prostate cancer both metastasize to bone in humans, but breast cancer typically induces osteolytic disease and prostate cancer typically induces osteoblastic metastases. The Rosol laboratory has developed mouse models of human cancer that mimic metastases in humans and are used to investigate the pathogenesis and treatment of metastasis. New laboratory expertise has been developed for in vivo imaging of cancer in mouse models using bioluminescence, high resolution ultrasound, and near infrared imaging of molecular markers. The lab is also examining the ability of nanoparticles to enhance the ultrasound imaging of cancer molecular markers.

Current Independent and Collaborative Research Interests:

ANIMAL MODELS OF HUMAN DISEASE:
Paraneoplastic Syndromes
Endocrinology
Bone Disease, Bone Remodeling, Bone Metastasis
Prostate Cancer and Osteoblastic Metastasis
Breast, Lung, and Head & Neck Cancer and Osteolytic Bone Metastasis

PARATHYROID HORMONE-RELATED PROTEIN (PTHrP):
Pathogenesis in humoral hypercalcemia of malignancy
Regulation in normal and neoplastic keratinocytes
Regulation in lactation and mammary carcinomas
Development of PTHrP knockout and knockin Mice
Regulation of mRNA expression and stability
Role in cancer metastases in bone
Role in bone resorption associated with Human T-Lymphotropic-I Virus infection and canine lymphoma
Regulation of PTHrP mRNA expression by Tax and HTLV-1 virus

GRADUATE STUDENTS AND POSTDOCTORALS MENTORED:
01. PostDoc, 1988-89, Shigeru Saito, DDS, ASSOCIATE PROFESSOR, Showa Univ. Japan
02. PostDoc, 1990-91, Rahima Nohutcu, DDS, PROFESSOR, Hacettepe Univ. Turkey
03. PhD, 1988-91, Laurie McCauley, DDS, PROFESSOR & CHAIRPERSON, Univ. of Michigan, supported by NIH NRSA (F32)
04. Dr.Med.Vet, 1990-92, Andrea Groene, DVM, ASSISTANT PROFESSOR, Univ. of Hannover
05. PostDoc, 1992-93, Hiroyuki Okada, DVM, PATHOLOGIST, National Institute of Animal Health, Tsukuba, Japan
06. PhD, 1987-93, Joyce Merryman, DVM, VETERINARIAN, Knoxville, Tennessee, supported by NIH NRSA (F32)
07. MS, 1992-95, James Werkmeister, DDS, PERIODONTIST, Pittsburgh, Pennsylvania, supported by NIH Career Award (K11)
08. MS, 1993-95, Michelle Weckmann, MD, MEDICAL INTERNIST, University of Iowa
09. PhD, 1992-96, Andrea Groene, DVM, ASSISTANT PROFESSOR, University of Hannover
10. PhD, 1995-98, Eric Blomme, DVM, TOXICOLOGICAL PATHOLOGIST, Abbott Labs., Chicago
11. PhD, 1994-99, Susan Wojcik, DVM, TOXICOLOGICAL PATHOLOGIST, Human Genome Sciences, Rockville, MD, supported by NIH NRSA (F32)
12. PostDoc, 1998, Shelley Kendrick, DVM
13. PhD, 1997-2001, Rani Sellers, DVM, TOXICOLOGICAL PATHOLOGIST, Hoffman-LaRoche, New York, supported by NIH NRSA (F32)
14. PhD and PostDoc, 1998-2005, Ramiro Toribio, DVM, RESEARCH SCIENTIST, Ohio State University, supported by NIH K01 Career Award
15. PhD, 1999-2002, Bruce LeRoy, DVM, ASSISTANT PROFESSOR, University of Georgia, supported by NIH NRSA (T32)
16. PhD, 1998-2003, Virgile Richard, DVM, TOXICOLOGICAL PATHOLOGIST, Pfizer Global Research & Development, Sandwich, England
17. PhD, 1998-2005, Sarah Tannehill-Gregg, DVM, PhD, TOXICOLOGICAL PATHOLOGIST, Bristol-Myers-Squibb, Supported by NIH K08 Career Award
18. PostDoc, 2001-2005, Alex Luchin, PhD, SCIENTIST, University of Vancouver
19. PostDoc, 2003-2005, Xiyun Deng, PhD, ASSISTANT PROFESSOR, Central South University, P.R.China
20. Research Scientist, 2003-2005, Jun Liu, PhD, ASSISTANT PROFESSOR, Ohio State University
21. PhD, 2002-2007, Martin Brena, BS, POSTDOC
22. PhD, 2002-2008, Prasad Nadella, BVSc, PATHOLOGIST, Covance, Madison, WI
23. PhD, 2003-present, Gwendolen Lorch, DVM, DACVIM (Dermatology), NRSA FELLOW (T32), NCRR K01 Awardee
24. PhD, 2004-present, Nanda Thudi, BVSc
25. Professor, 2003-2008, Alicia Bertone, DVM, PhD, CO-MENTOR FOR NIH CAREER AWARD (K08)
26. PhD, 2004-present, Chelsea Martin, DVM, Individual NRSA Fellow (F32)
27. PhD, 2005-present, Jillian Werbec, BS (Dept of Defense Fellow)
28. PhD, 2006-present, Sherry Shu, BVM, NRSA Fellow (T32)
29. PhD, 2006-present, Shanmugam Naidu, BVSc, MS
30. PhD, 2007-present, Lisa (Gooding) Lanigan, DVM, NRSA fellow (T32)
31. Research Scientist, 2007 - present, John Leong, PhD
32. PhD, Blake Eason Hildreth III, DVM, MS, 2008 - present

Undergraduate Mentoring: 16 students

Graduate Student Exam Committees: >50 PhD & MS students

Other Expertise

Diplomate of the American College of Veterinary Pathologists (ACVP)
Fellow, American Association for the Advancement of Science

Boards and Councils:
2008-present: External Advisory Board, North Carolina State University Center for Comparative Medicine and Translational Research
2007-2011: NIH Council, National Center for Research Resources (NCRR) Advisory Board
2008-2010: USDA Advisory Board, National Agricultural Research, Extension, Education, and Economics Advisory Board (NAREEEAB)
2007-present: Board of Scientific Advisors, Pathology Experts, LLC (Basel)
2006-2011: External Advisory Board, University of Michigan NIH Program Project Grant on Skeletal Metastases
2006-present: Board of Trustees, The Wilds (conservation of exotic animals)
2005-2008: Board of Trustees (ex officio), Ohio Veterinary Medical Association
2005-2008: Board of Trustees (ex officio), Ohio Livestock Coalition
2005-2008: Board of Trustees, OSU College of Veterinary Medicine Alumni Society
2003-2004: Board of Trustees, Scitech (Science Research & Technology Park for OSU)
2003-2004: Board of Trustees (President), Ohio State University Research Foundation Board
2003-2004: Council for Higher Education, Ohio Board of Regents
2003-2004: Governing Board, Ohio Supercomputer Center
2003-2004: Board of Trustees, Edison Welding Institute
2003-2004: Board of Directors, Ohio Aerospace Institute (OAI)
2003-2004: Ohio Polymer Strategy Council
2003-2004: Board of Directors, Transportation Research Center
2003-2004: Council on Research Policy and Graduate Education (CRPG, NASULGC)
2003-2004: Committee on Institutional Cooperation (CIC) for Senior Research Officers

Future Research

Current Independent and Collaborative Research Interests:

ANIMAL MODELS OF HUMAN DISEASE:
Paraneoplastic Syndromes
Endocrinology
Bone Disease, Bone Remodeling, Bone Metastasis
Prostate Cancer and Osteoblastic Metastasis
Breast Cancer and Bone Metastasis

PARATHYROID HORMONE-RELATED PROTEIN (PTHrP):
Pathogenesis in humoral hypercalcemia of malignancy
Regulation in normal and neoplastic keratinocytes
Regulation in lactation and mammary carcinomas
Development of a Cre/LoxP Mammary Gland Specific "Knock-out" Transgenic Mice
Regulation of mRNA expression and stability by transforming growth factor-beta
Role in cancer metastases in bone
Role in bone resorption associated with Human T-Lymphotropic-I Virus infection and canine lymphoma
Regulation of PTHrP mRNA expression by Tax and HTLV-1 virus

Industrial Relevance

Consultation in Toxicological & Veterinary Pathology:
Endocrine Diseases
Bone Pathobiology
Reproductive Diseases
Cancer and Animal Models of Human Disease
Veterinary Pathology
Surgical Pathology

Keywords

COS Keywords:

Animal Development, Animal Diseases Or Pathology, Animal Models, Animal Physiology Or Morphology, Bone Diseases, Breast Cancer, Canine Diseases Or Pathology, Cell Biology, Cytokines, Cytopathology, Dairy Science, Endocrinology, Equine Diseases Or Pathology, Equine Studies, Life Sciences, Lung Cancer, Metabolic Biology, Metastasis, Molecular Biology, Molecular Genetics, Osteology Or Osteopathy, Pathobiology, Pathology, Prostate Cancer, Surgery, Urology, Veterinary Medicine, Veterinary Toxicology.

Additional Terms:

Animal Model, Bone Disease, Bone Histomorphometry, Calcium, Carcinoma, Endocrinology, Humoral Hypercalcemia of Malignancy, Hypercalcemia, Mammary Gland, Metastasis, Parathryoid Hormone-Related Protein, Parathyroid, Pathology, Veterinary Pathology.

Memberships

American Association for Cancer Research

American Association for the Advancement of Science

American College of Veterinary Pathologists

American Society for Bone and Mineral Research

American Veterinary Medical Association

Charles Louis Davis, Doctoral of Veterinary Medicine Foundation

Comparative Endocrinology of Calcium Regulation (Organizing Committee)

European Calcified Tissue Society

Gamma Sigma Delta

International Bone and Mineral Society

Phi Kappa Phi

Phi Zeta

Society of Toxicologic Pathologists

Honors and Awards

2007, Dr. Erwin Small Distinguished Alumnus Award, College of Veterinary Medicine, University of Illinois at Urbana-Champaign

2006, Distinguished Scholar Award, The Ohio State University

2004, Fellow, American Association for the Advancement of Science (AAAS)

2004, Research Award for High Quality Publications in Molecular Carcinogenesis and Chemoprevention, Comprehensive Cancer Center, Ohio State University

2003, H.W. Casey Scholarship Award, Faculty Advisor of Sarah Tannehill-Gregg, DVM, American College of Veterinary Pathologists, The annual national award recognizes an outstanding trainee in veterinary pathology

2001-2004, David White Research Award, College of Veterinary Medicine, Ohio State University

2000-2005, Research Midcareer Development Award, National Center for Research Resources, The National Institutes of Health

1999, H.W. Casey Scholarship Award, Faculty Advisor of Rani Sellers, DVM, American College of Veterinary Pathologists, American College of Veterinary Pathologists, The annual national Award recognizes an outstanding trainee in veterinary pathology

1998, Academy of Teaching Excellence, College of Veterinary Medicine, Ohio State University

1998, Dean's Teaching Excellence Award for Graduate Education, College of Veterinary Medicine, Ohio State University

1996, H.W. Casey Scholarship Award, Faculty Advisor of Andrea Groene, DVM, Ph.D., American College of Veterinary Pathologists, The annual national award recognizes an outstanding trainee in veterinary pathology

1993-1998, Research Career Development Award, National Institute of Arthritis and Musculoskeletal and Skin Diseases, The National Institutes of Health

1991, Smithkline-Beecham Award for Research Excellence, College of Veterinary Medicine, Ohio State University

1985-1988, National Research Service Award, National Cancer Institute, The National Instititutes of Health

1985-1987, Research Fellow, Morris Animal Foundation

1985, Veterinary Pathology Scholarship Award, C.L. Davis, D.V.M. Foundation

1983-1985, Research Fellow, Schering Plough Corporation Foundation, Ohio State University

1981, Valedictiorian of Graduating Class, College of Veterinary Medicine, University of Illinois at Urbana-Champaign

1979, Jesse Sampson Physiology Award, College of Veterinary Medicine, University of Illinois at Urbana-Champaign

1978, Merck Veterinary Manual Award, College of Veterinary Medicine, University of Illinois at Urbana-Champaign

1977, Animal Science Scholarship Award, College of Agriculture, University of Illinois at Urbana-Champaign

Previous Positions

2005-2008, Dean, Ohio State University, College of Veterinary Medicine

2004-2005, Senior Associate Vice President for Research, Ohio State University

2003-2004, Interim Vice President, Ohio State University, Research

2002-2003, Senior Associate Vice President for Research, Ohio State University

1991-1996, Associate Professor, Ohio State University, College of Veterinary Medicine, Veterinary Biosciences

1986-1991, Assistant Professor, Ohio State University, Veterinary Pathobiology

1983-1986, Research Fellow, Ohio State University, Veterinary Pathobiology

1981-1983, Veterinary Practitioner, Lancaster Veterinary Hospital (Wisconsin)

Funding Received

NIH: National Cancer Institute (P01 CA1007730, Project 4): Role of bone microenvironment in Tax-induced malignancies, $1,658,108, 2008 to 2013.

DOD: US Army Medical Research (Mentor for Jillian Werbeck, BS): Ets2 contributions of the tumor microenvironment in breast cancer metastasis, $97,010, 2008 to 2011.

NIH: National Cancer Institute (F32 CA130458) (Mentor for Chelsea Martin, DVM): Mechanisms of bone invasion and tumor growth in models of head and neck cancer, $190,158, 2007 to 2010.

Susan G. Komen Breast Cancer Foundation: Intravasation genes of human breast cancer, $240,000, 2007 to 2009.

NIH: National Center for Research Resources (T32 RR07073-06): Mouse Pathobiology: Models of Human Disease, $1,958,084, 2007 to 2012.

NIH: National Center for Research Resources (K01; RR021879) (Mentor for G. Lorch, DVM): Regulation of PTHrP in Squamous Cell Carcinoma by EGF Receptor, $587,500, 2006 to 2011.

NIH; National Center for Research Resources (K01; RR021879) (Mentor for Ramiro Toribio, DVM, PhD): PTHrP on Normal Osteoblast Differentiation and Function, $638,000, 2005 to 2009.

Susan G. Komen Breast Cancer Foundation (Co-I): Imaging Breast Cancer Markers with Nanoparticle Enhanced Ultrasound, $249,604, 2005 to 2007.

NIH; National Cancer Institute (Co-I): HER2/Neu and Dietary Fat: Gene Nutrient Interactions in Breast Cancer, $411,125, 2005 to 2007.

NIH: NIDDK (Co-I): Erb1 Signaling and Cancer-Mediated Diseases of Bone, $200,000, 2005 to 2007.

NIH; National Cancer Institute (P01 CA097189) (Core Leader): Role of Stroma in Breast Cancer Progression; Leader of Core B: Mouse Pathology, $728,251, 2004 to 2009.

Morris Animal Foundation (03FE-29) (PI): Oral Squamous Cell Carcinoma in Cats: Preclinical Therapy and Inhibition of Bone Resorption, $191,552, 2004 to 2007.

OSU College of Veterinary Medicine Glenn Barber Fellowship for Prasad Nadella, BVSc: Role of Parathyroid Hormone-Related Protein in the Pathogenesis of Lymphoma (Mentor and PI), $113,900, 2004 to 2007.

NIH: National Cancer Institute (P01 CA100730); PI of Project 4: PTHrP in HTLV-1-Induced Lymphoma/Leukemia (Project Leader for project 4), $1,209,604, 2003 to 2008.

NIH: National Cancer Institute (P01 CA100730); Leader for Animal Model Core: PTHrP in HTLV-1-Induced Lymphoma/Leukemia (Animal Model Core Leader), $1,150,778, 2003 to 2008.

NIH: NCI Comprehensive Cancer Center Core Grant Supplement: High Resolution Ultrasound Imaging System (Vevo 660) (PI), $167,000, 2003 to .

NIH: National Center for Research Resources (S10 RR17841): Measurement of Cells In Vivo: IVIS Light Imaging System (PI), $169,950, 2003 to 2004.

NIH: National Center for Research Resources (T32 RR07073): Mouse Pathobiology: Models of Human Disease (Training Grant Program Director), $1,307,760, 2002 to 2007.

Schering Plough Research Institute: Effect of SCH488900 on Prostate Volume in Dogs with Benign Prostatic Hyperplasia (PI), $249,703, 2002 to 2004.

Pharmacia Company: Effect of Oxazolidones on Osteoblasts and Bone Marrow Stromal Cells In Vitro (PI), $34,224, 2001 to 2002.

NIH: National Center for Research Resources (K26 RR00168): Mouse Models of Cancer, Bone Disease, and Lactation (Midcareer Award), $546,629, 2000 to 2005.

NIH: National Cancer Institute (K08 CA83766): Lung Cancer: Role of PTHrP and regulation by TGF-beta (Mentor for K08 for Sarah Tannehill-Gregg, DVM), $508,579, 2000 to 2005.

Ohio State University Comprehensive Cancer Center: Role of Endothelin-1 in Bone Formation Induced by Normal and Neoplastic Prostate Epithelium (PI), $10,000, 2000 to .

NIH: NCI (Supplement to R01 CA77911): PTHrP and TGF-beta in SCID/beige Mice with Human Cancer (PI), $91,667, 1999 to 2002.

NIH: National Cancer Institute (T32 CA09338): Pathogenesis of Osteoblastic Metastases in Human Prostate Cancer (Mentor for NRSA for Bruce LeRoy, DVM), $75,145, 1999 to 2002.

Ohio State University College of Veterinary Medicine - Glenn Barber Funds for Graduate Student Stipend: Regulation of PTH and pathogenesis of hypocalcemia during endotoxemia (Mentor for Ramiro Toribio), $78,000, 1999 to 2002.

NIH: National Cancer Institute (R01 CA77911): Regulation of PTGrP in Squamous Cell Carcinoma by TGF- beta (PI), $717,481, 1998 to 2003.

NIH: National Cancer Institute (F32 CA79110): Head and Neck Cancer: The Role of TGF-beta and PTHrP (Mentor for NRSA for Rani Sellers, DVM), $117,852, 1998 to 2001.

Equine Research Funds State of Ohio: Measurement of parathyroid gland function and chief cell calcium set-point in healthy horses and horses with enterocolitis (PI), $14,988, 1998 to 1999.

USDA: CREES (9703625): Role of parathyroid hormone-related protein in lactation and neonatal development (PI), $166,667, 1997 to 1999.

Equine Research Funds State of Ohio: Pathogenesis of hypocalcemia in horses with toxic colitis (PI), $14,718, 1997 to 1999.

Canine Research Funds State of Ohio: Regulation of parathyroid hormone-related protein in canine squamous cell carcinoma (PI), $11,970, 1997 to 1999.

Columbus Zoo: Calcium-regulating hormones and bone remodeling in green iguanas (PI), $9,969, 1997 to 1998.

NIH: NIDDK (F32 DK09294): Parathyroid hormone-related protein in the Mammary Gland (Mentor for NRSA for Susan Wojcik, DVM), $93,600, 1996 to 1999.

Canine Research Funds State of Ohio: Isolation of the Genomic Promoter for Canine PTHrP and Analysis of its Activation in a Canine Squamous Carcinoma Cell Line (PI), $11,690, 1995 to 1997.

United States Department of Agriculture (USDA): Parathyroid Hormone-Related Protein and the Lactating Bovine Mammary Gland (PI), $14,900, 1994 to .

Glen Barber Fund - The Ohio State University: Proteolytic Cleavage of Parathyroid Hormone-Related Protein at Sites of Basic Amino Acids (Fellowship for Andrea Groene, DVM), $88,450, 1993 to 1996.

Canine Research Funds State of Ohio: Effects of Transforming Growth Factor-beta on Parathyroid Hormone-Related Protein Expression in Canine Squamous Cell Carcinoma (PI), $9,200, 1993 to 1995.

NIH: NCRR (S15 CA62305): Small Instrument Grant: Zeiss Cryosat (PI), $16,235, 1993 to .

NIH: Natl Inst Arthritis & Musculoskeletal Diseases (K04 AR01923): PTHrP in Normal and Neoplastic Keratinocytes (Research Career Award), $300,250, 1993 to 1998.

NIH: Natl Inst for Dental Research (K11 DE00321): Regulation of Parathyroid Hormone-Related Protein (Mentor for K11 award for James Werkmeister, DDS), $402,453, 1992 to 1995.

NIH: Natl Inst of Arthritis & Musculoskeletal & Skin Diseases (R29 AR40220): Humoral Factor Interactions in Hypercalcemia of Cancer (PI), $349,000, 1992 to 1997.

Pharmaceutical Manufacturers Association Foundation: Effects of Mithramycin on Bone Metabolism In Vivo and In Vitro (PI), $60,000, 1991 to 1993.

Canine Research Funds (Ohio State Universtiy College of Veterinary Medicine): Characterization of Hypercalcemic Factors in Humoral Hypercalcemia of Malignancy in Dogs (PI), $12,570, 1991 to 1993.

Hildegard Doerenkamp Foundation, Zurich, Switzerland: Investigations of Cancer of the Terminal Intestine in Dogs (co-PI), $72,500, 1991 to 1992.

American Animal Hospital Association Foundation: Treatment of Hypercalcemia of Cancer in Dogs (PI), $10,000, 1991 to 1992.

Canine Research Funds , Ohio State Universtiy College of Veterinary Medicine: Control of Canine Parathyroid Hormone-Related Protein Synthesis and Secretion (PI), $19,535, 1990 to 1992.

American Fund for Dental Health: Training fellowship for Laurie K. McCauley, DDS; PhD candidate, $20,000, 1990 to 1991.

Ohio State University Research Challenge Grant: Identification and Production of cDNA Probes for Canine Parathyroid Hormone-Related Protein (PI), $10,906, 1990 to .

American Cancer Society, The Ohio State University, Comprehensive Cancer Center: Transforming Growth Factors and Hypercalcemia of Cancer (PI), $10,000, 1989 to 1990.

Elsa U. Pardee Foundation: Role of Parathyroid Hormone-Related Protein in the Pathogenesis of Humoral Hypercalcemia of Malignancy (PI), $53,320, 1989 to 1990.

Ohio State University Research Challenge: Effects of Infusion of Human Parathyroid Hormone-Related Protein(1-40) in Nude Mice (PI), $9,000, 1988 to 1989.

Canine Research Funds (OSU): Identification of Hypercalcemic Proteins and Immunodiagnosis of Humoral Hypercalcemia of Malignancy in the Dog (PI), $25,000, 1988 to 1990.

Ohio State University Seed Grant: Characterization of Humoral Factors Associated with Humaral Hypercalcemia of Malignancy (PI), $15,000, 1987 to .

NIH: National Cancer Institute (F32 CA07818): Pathogenesis of Humoral Hypercalcemia of Malignancy (Individual NRSA for Thomas Rosol), $90,000, 1985 to 1988.

Morris Animal Foundation: Treatment of Humoral Hypercalcemia of Malignancy in Dogs (PI), $36,500, 1985 to 1987.

Schering-Plough Foundation: Fellowship in Veterinary Pathology for Thomas Rosol, $30,000, 1983 to 1985.

Publications

Pinzone JJ, Hall BM, Thudi NK, Vonau M, Qiang YW, Rosol TJ, Shaughnessy Jr JD (Aug 2008) The role of Dickkopf-1 in bone development, homeostasis and disease., Blood
Liao J, Li X, Koh AJ, Berry JE, Thudi N, Rosol TJ, Pienta KJ, McCauley LK (Aug 2008) Tumor expressed PTHrP facilitates prostate cancer-induced osteoblastic lesions., International journal of cancer. Journal international du cancer
Thudi NK, Martin CK, Nadella MV, Fernandez SA, Werbeck JL, Pinzone JJ, Rosol TJ (Jul 2008) Zoledronic acid decreased osteolysis but not bone metastasis in a nude mouse model of canine prostate cancer with mixed bone lesions., The Prostate, 68 (10), 1116-25
Tsai SY, Opavsky R, Sharma N, Wu L, Naidu S, Nolan E, Feria-Arias E, Timmers C, Opavska J, de Bruin A, Chong JL, Trikha P, Fernandez SA, Stromberg P, Rosol TJ, Leone G (Jun 2008) Mouse development with a single E2F activator., Nature
Lairmore M, Rosol T (May 2008) Dr. Charles C. Capen--an enduring legacy in veterinary pathology., Veterinary pathology, 45 (3), 285-6
Trimboli AJ, Fukino K, de Bruin A, Wei G, Shen L, Tanner SM, Creasap N, Rosol TJ, Robinson ML, Eng C, Ostrowski MC, Leone G (Feb 2008) Direct evidence for epithelial-mesenchymal transitions in breast cancer., Cancer research, 68 (3), 937-45
Nadella MV, Shu ST, Dirksen WP, Thudi NK, Nadella KS, Fernandez SA, Lairmore MD, Green PL, Rosol TJ (2008) Expression of parathyroid hormone-related protein during immortalization of human peripheral blood mononuclear cells by HTLV-1: implications for transformation., Retrovirology, 5, 46
Nadella MVP, Kisseberth WC, Nadella KS, Thudi TK, Thamm DH, McNeil EA, Yilmaz A, Boris-Lawrie K, Rosol TJ (2008) NOD/SCID mouse model of canine T-cell lymphoma with humoral hypercalcemia of malignancy: cytokine gene expression profiling and in vivo bioluminescent imaging, Veterinary and Comparative Oncology, 6 (1), 39-54
Shu ST, Nadella MV, Dirksen WP, Fernandez SA, Thudi NK, Werbeck JL, Lairmore MD, Rosol TJ (Dec 2007) A novel bioluminescent mouse model and effective therapy for adult T-cell leukemia/lymphoma., Cancer research, 67 (24), 11859-66
Kisseberth WC, Nadella MV, Breen M, Thomas R, Duke SE, Murahari S, Kosarek CE, Vernau W, Avery AC, Burkhard MJ, Rosol TJ (Dec 2007) A novel canine lymphoma cell line: a translational and comparative model for lymphoma research., Leukemia research, 31 (12), 1709-20
Liu J, Li J, Rosol TJ, Pan X, Voorhees JL (Aug 2007) Biodegradable nanoparticles for targeted ultrasound imaging of breast cancer cells in vitro., Physics in medicine and biology, 52 (16), 4739-47
Nadella MV, Dirksen WP, Nadella KS, Shu S, Cheng AS, Morgenstern JA, Richard V, Fernandez SA, Huang TH, Guttridge D, Rosol TJ (Aug 2007) Transcriptional regulation of parathyroid hormone-related protein promoter P2 by NF-kappaB in adult T-cell leukemia/lymphoma., Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, 21 (8), 1752-62
Lorch G, Gilmore JL, Koltz PF, Gonterman RM, Laughner R, Lewis DA, Konger RL, Nadella KS, Toribio RE, Rosol TJ, Foley J (Jul 2007) Inhibition of epidermal growth factor receptor signalling reduces hypercalcaemia induced by human lung squamous-cell carcinoma in athymic mice., British journal of cancer, 97 (2), 183-93
Toribio RE, Kohn CW, Rourke KM, Levine AL, Rosol TJ (May 2007) Effects of hypercalcemia on serum concentrations of magnesium, potassium, and phosphate and urinary excretion of electrolytes in horses., American journal of veterinary research, 68 (5), 543-54
Alvarez FJ, Murahari S, Couto CG, Rosol TJ, Kulp SK, Chen CS, Kisseberth WC (2007) Phosphoinositide-dependent protein kinase-1 (PDK-1)/Akt signaling and inhibition in a canine prostate carcinoma cell line, Veterinary and Comparative Oncology, 5, 47-58
Deng X, Tannehill-Gregg SH, Nadella MV, He G, Levine A, Cao Y, Rosol TJ (2007) Parathyroid hormone-related protein and ezrin are up-regulated in human lung cancer bone metastases., Clinical & experimental metastasis, 24 (2), 107-19
Lairmore MD, Oglesbee M, Weisbrode SE, Wellman M, Rosol T, Stromberg P (2007) Developing and fostering a dynamic program for training in veterinary pathology and clinical pathology: veterinary students to post-graduate education., Journal of veterinary medical education, 34 (4), 464-72
Heller DA, Fan TM, de Lorimier LP, Charney SC, Barger AM, Tannehill-Gregg SH, Rosol TJ, Wallig MA (2007) In vitro cyclooxygenase-2 protein expression and enzymatic activity in neoplastic cells., Journal of veterinary internal medicine / American College of Veterinary Internal Medicine, 21 (5), 1048-55
Jia G, Heverhagen JT, Polzer H, Jacko RV, Liang J, Zhang J, Levine AL, Rosol TJ, Knopp MV (Nov 2006) Dynamic contrast enhanced magnetic resonance imaging as a biological marker to noninvasively assess the effect of finasteride on prostatic suburethral microcirculation., The Journal of urology, 176 (5), 2299-304
Halvorson KG, Sevcik MA, Ghilardi JR, Rosol TJ, Mantyh PW (Sep 2006) Similarities and differences in tumor growth, skeletal remodeling and pain in an osteolytic and osteoblastic model of bone cancer., The Clinical journal of pain, 22 (7), 587-600
LeRoy BE, Thudi NK, Nadella MV, Toribio RE, Tannehill-Gregg SH, van Bokhoven A, Davis D, Corn S, Rosol TJ (Aug 2006) New bone formation and osteolysis by a metastatic, highly invasive canine prostate carcinoma xenograft., The Prostate, 66 (11), 1213-22
Jia G, Heverhagen JT, Henry H, Polzer H, Baudendistel KT, von Tengg-Kobligk H, Levine AL, Rosol TJ, Knopp MV (Jul 2006) Pharmacokinetic parameters as a potential predictor of response to pharmacotherapy in benign prostatic hyperplasia: a preclinical trial using dynamic contrast-enhanced MRI., Magnetic resonance imaging, 24 (6), 721-5
Liu J, Levine AL, Mattoon JS, Yamaguchi M, Lee RJ, Pan X, Rosol TJ (May 2006) Nanoparticles as image enhancing agents for ultrasonography., Physics in medicine and biology, 51 (9), 2179-89
Tannehill-Gregg SH, Levine AL, Rosol TJ (2006) Feline head and neck squamous cell carcinoma: A natural model for the human disease and development of a mouse model, Veterinary and Comparative Oncology, 4 (2), 84-97
Tannehill-Gregg SH, Levine AL, Nadella MV, Iguchi H, Rosol TJ (2006) The effect of zoledronic acid and osteoprotegerin on growth of human lung cancer in the tibias of nude mice., Clinical & experimental metastasis, 23 (1), 19-31
Halvorson KG, Kubota K, Sevcik MA, Lindsay TH, Sotillo JE, Ghilardi JR, Rosol TJ, Boustany L, Shelton DL, Mantyh PW (Oct 2005) A blocking antibody to nerve growth factor attenuates skeletal pain induced by prostate tumor cells growing in bone., Cancer Research, 65 (20), 9426-35
Richard V, Nadella MV, Green PL, Lairmore MD, Feuer G, Foley JG, Rosol TJ (Jul 2005) Transcriptional regulation of parathyroid hormone-related protein promoter P3 by ETS-1 in adult T-cell leukemia/lymphoma., Leukemia : Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.k., 19 (7), 1175-83
Yee LD, Young DC, Rosol TJ, Vanbuskirk AM, Clinton SK (May 2005) Dietary (n-3) polyunsaturated fatty acids inhibit HER-2/neu-induced breast, The Journal of Nutrition, 135 (5), 983-8
Jia G, Baudendistel KT, von Tengg-Kobligk H, Heverhagen JT, Polzer H, Henry H, McAuliffe MJ, Levine AL, Rosol TJ, Knopp MV, Assessing Prostate Volume By Magnetic Resonance Imaging: a Comparison Of Different Measurement Approaches for Organ Volume Analysis., Investigative Radiology, 40(4), 243-8, Apr 2005
Richard V, Rosol TJ, Foley J (2005) PTHrP gene expression in cancer: Do all paths lead to ets?, Critical Reviews in Eukaryotic Gene Expression, 15, 115-132
Toribio RE, Kohn CW, Hardy J, Rosol TJ, Alterations in Serum Parathyroid Hormone and Electrolyte Concentrations and Urinary Excretion of Electrolytes in Horses With Induced Endotoxemia., Journal of Veterinary Internal Medicine / American College of Veterinary Internal Medicine., 19(2), 223-31, Mar-Apr 2005
Heverhagen JT, von Tengg-Kobligk H, Baudendistel KT, Jia G, Polzer H, Henry H, Levine AL, Rosol TJ, Knopp MV, Benign prostate hyperplasia: evaluation of treatment response with DCE MRI, Magma (New York, N.Y.), 17(1), 5-11, Sep 2004
Sankar U, Patel K, Rosol TJ, Ostrowski MC, RANKL coordinates cell cycle withdrawal and differentiation in osteoclasts through the cyclin-dependent kinase inhibitors p27KIP1 and p21CIP1, Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research., 19(8), 1339-48, August 2004
Sellers RS, Luchin AI, Richard V, Brena RM, Lima D, Rosol TJ, Alternative splicing of parathyroid hormone-related protein mRNA: expression and stability, Journal of Molecular Endocrinology, 33(1), 227-41, August 2004
LeRoy BE, Sellers RS, Rosol TJ, Canine prostate stimulates osteoblast function using the endothelin receptors, The Prostate, 59(2), 148-56, May 2004
Tannehill-Gregg SH, Kusewitt DF, Rosol TJ, Weinstein M, The roles of Smad2 and Smad3 in the development of chemically induced skin tumors in mice, Veterinary Pathology, 41(3), 278-82, May 2004
Kunakornsawat S, Rosol TJ, Capen CC, Omdahl JL, Leroy BE, Inpanbutr N, Effects of 1,25(OH)2D3, 25OHD3, and EB1089 on cell growth and Vitamin D receptor mRNA and 1alpha-hydroxylase mRNA expression in primary cultures of the canine prostate, The Journal of Steroid Biochemistry and Molecular Biology, 89-90(1-5), 409-12, May 2004
Cho YM, Lewis DA, Koltz PF, Richard V, Gocken TA, Rosol TJ, Konger RL, Spandau DF, Foley J, Regulation of parathyroid hormone-related protein gene expression by epidermal growth factor-family ligands in primary human keratinocytes, Journal of Endocrinology, 181(1), 179-90, April 2004
Dai Z, Popkie AP, Zhu WG, Timmers CD, Raval A, Tannehill-Gregg S, Morrison CD, Auer H, Kratzke RA, Niehans G, Amatschek S, Sommergruber W, Leone GW, Rosol T, Otterson GA, Plass C, Bone morphogenetic protein 3B silencing in non-small-cell lung cancer, Oncogene, 23(20), 3521-9, April 2004
Sellers RS, LeRoy BE, Blomme EA, Tannehill-Gregg S, Corn S, Rosol TJ, Effects of transforming growth factor-beta1 on parathyroid hormone-related protein mRNA expression and protein secretion in canine prostate epithelial, stromal, and carcinoma cells, The Prostate, 58(4), 366-73, March 2004
LeRoy BE, Nadella MV, Toribio RE, Leav I, Rosol TJ, Canine prostate carcinomas express markers of urothelial and prostatic differentiation, Veterinary Pathology, 41(2), 131-40, March 2004
Rosol TJ, Tannehill-Gregg SH, Corn S, Schneider A, McCauley LK, Animal models of bone metastasis, Cancer Treatment and Research, 118, 47-81, 2004
Toribio RE, Kohn CW, Capen CC, Rosol TJ, Parathyroid hormone (PTH) secretion, PTH mRNA and calcium-sensing receptor mRNA expression in equine parathyroid cells, and effects of interleukin (IL)-1, IL-6, and tumor necrosis factor-a, Journal of Molecular Endocrinology, 31(3), 609-20, December 2003
Kalikin LM, Schneider A, Thakur MA, Fridman Y, Griffin LB, Dunn RL, Rosol TJ, Shah RB, Rehemtulla A, McCauley LK, Pienta KJ, In vivo visualization of metastatic prostate cancer and quantitation of disease progression in immunocompromised mice, Cancer Biology & Therapy, 2(6), 656-60, 2003
Richard V, Luchin A, Brena RM, Plass C, Rosol TJ, Quantitative evaluation of alternative promoter usage and 3' splice variants for parathyroid hormone-related protein by real-time reverse transcription-PCR, Clinical Chemistry, 49(8), 1398-402, August 2003
de Bruin A, Wu L, Saavedra HI, Wilson P, Yang Y, Rosol TJ, Weinstein M, Robinson ML, Leone G, Rb function in extraembryonic lineages suppresses apoptosis in the CNS of Rb-deficient mice, Proceedings of the National Academy of Sciences of the United States of America., 100(11), 6546-51, May 2003
Toribio RE, Kohn CW, Sams RA, Capen CC, Rosol TJ, Hysteresis and calcium set-point for the calcium parathyroid hormone relationship in healthy horses, General and Comparative Endocrinology, 130(3), 279-88, February 2003
Rosol TJ, Tannehill-Gregg SH, LeRoy BE, Mandl S, Contag CH, Animal models of bone metastasis, Cancer, 97(3 Suppl), 748-57, February 2003
Wu L, de Bruin A, Saavedra HI, Starovic M, Trimboli A, Yang Y, Opavska J, Wilson P, Thompson JC, Ostrowski MC, Rosol TJ, Woollett LA, Weinstein M, Cross JC, Robinson ML, Leone G, Extra-embryonic function of Rb is essential for embryonic development and viability, Nature, 421(6926), 942-7, February 2003
Toribio RE, Kohn CW, Leone GW, Capen CC, Rosol TJ, Molecular cloning and expression of equine calcitonin, calcitonin gene-related peptide-I, and calcitonin gene-related peptide-II, Molecular and Cellular Endocrinology, 199(1-2), 119-28, January 2003
McCauley LK, Tozum TF, Kozloff KM, Koh-Paige AJ, Chen C, Demashkieh M, Cronovich H, Richard V, Keller ET, Rosol TJ, Goldstein SA, Transgenic models of metabolic bone disease: impact of estrogen receptor deficiency on skeletal metabolism, Connective Tissue Research, 44 Suppl 1, 250-63, 2003
LeRoy BE, Bahnson RR, Rosol TJ, New bone formation in nude mouse calvaria induced by canine prostate tissue, Molecular and Cellular Endocrinology, 197(1-2), 257-63, November 2002
Kiku Y, Matsuzawa H, Ohtsuka H, Terasaki N, Fukuda S, Kon-Nai S, Koiwa M, Yokomizo Y, Sato H, Rosol TJ, Okada H, Yoshino TO, Effects of chlorpromazine, pentoxifylline and dexamethasone on mRNA expression of lipopolysaccharide-induced inflammatory cytokines in bovine peripheral blood mononuclear cells, The Journal of Veterinary Medical Science / the Japanese Society of Veterinary Science., 64(8), 723-6, Aug 2002
Pressler BM, Rotstein DS, Law JM, Rosol TJ, LeRoy B, Keene BW, Jackson MW, Hypercalcemia and high parathyroid hormone-related protein concentration associated with malignant melanoma in a dog, Journal of the American Veterinary Medical Association, 221(2), 263-5, 240, July 2002
Liu Y, Dole K, Stanley JR, Richard V, Rosol TJ, Ratner L, Lairmore M, Feuer G, Engraftment and tumorigenesis of HTLV-1 transformed T cell lines in SCID/bg and NOD/SCID mice, Leukemia Research, 26(6), 561-7, June 2002
Grone A, McCauley LK, Capen CC, Rosol TJ, Cloning and sequencing of the 3'-region of the canine parathyroid hormone-related protein gene and analysis of alternate mRNA splicing in two canine carcinomas, Domestic Animal Endocrinology, 22(3), 169-77, May 2002
Kunakornsawat S, Rosol TJ, Capen CC, Reddy GS, Binderup L, Inpanbutr N, Effects of 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] and its analogues (EB1089 and analog V) on canine adenocarcinoma (CAC-8) in nude mice, Biological & Pharmaceutical Bulletin, 25(5), 642-7, May 2002
Saavedra HI, Wu L, de Bruin A, Timmers C, Rosol TJ, Weinstein M, Robinson ML, Leone G, Specificity of E2F1, E2F2, and E2F3 in mediating phenotypes induced by loss of Rb, Cell Growth & Differentiation : the Molecular Biology Journal of the American Association for Cancer Research., 13(5), 215-25, May 2002
LeRoy BE, Bahnson RR, Rosol TJ, Canine prostate induces new bone formation in mouse calvaria: A model of osteoinduction by prostate tissue, The Prostate, 50(2), 104-11, February 2002
Sellers RS, Capen CC, Rosol TJ, Messenger RNA stability of parathyroid hormone-related protein regulated by transforming growth factor-beta1, Molecular and Cellular Endocrinology, 188(1-2), 37-46, February 2002
Toribio RE, Kohn CW, Chew DJ, Capen CC, Rosol TJ, Cloning and sequence analysis of the complementary DNA for feline preproparathyroid hormone, American Journal of Veterinary Research, 63(2), 194-7, February 2002
McCauley LK, Tozum TF, Rosol TJ, Estrogen receptors in skeletal metabolism: lessons from genetically modified models of receptor function, Critical Reviews in Eukaryotic Gene Expression, 12(2), 89-100, 2002
Bolliger AP, Graham PA, Richard V, Rosol TJ, Nachreiner RF, Refsal KR, Detection of parathyroid hormone-related protein in cats with humoral hypercalcemia of malignancy, Veterinary Clinical Pathology / American Society for Veterinary Clinical Pathology., 31(1), 3-8, 2002
Tannehill-Gregg S, Kergosien E, Rosol TJ, Feline head and neck squamous cell carcinoma cell line: characterization, production of parathyroid hormone-related protein, and regulation by transforming growth factor-beta, In Vitro Cellular & Developmental Biology. Animal, 37(10), 676-83, 2001
Kunakornsawat S, Rosol TJ, Capen CC, Middleton RP, Hannah SS, Inpanbutr N, Effects of 1,25(OH)2D3, EB1089, and analog V on PTHrP production, PTHrP mRNA expression and cell growth in SCC 2/88, Anticancer Research, 21(5), 3355-63, 2001
Luchin A, Suchting S, Merson T, Rosol TJ, Hume DA, Cassady AI, Ostrowski MC, Genetic and physical interactions between Microphthalmia transcription factor and PU.1 are necessary for osteoclast gene expression and differentiation, Journal of Bioligical Chemistry, 276(39), 36703-10, September 2001
Toribio RE, Kohn CW, Chew DJ, Sams RA, Rosol TJ, Comparison of serum parathyroid hormone and ionized calcium and magnesium concentrations and fractional urinary clearance of calcium and phosphorus in healthy horses and horses with entero, American Journal of Veterinary Research, 62(6), 938-47, June 2001
Richard V, Lairmore MD, Green PL, Feuer G, Erbe RS, Albrecht B, D'Souza C, Keller ET, Dai J, Rosol TJ, Humoral hypercalcemia of malignancy: severe combined immunodeficient/beige mouse model of adult T-cell lymphoma independent of human T-cell lymphotropic virus type-1 tax expression, American Journal of Pathology, 158(6), 2219-28, June 2001
Rosol TJ, Yarrington JT, Latendresse J, Capen CC, Adrenal gland: structure, function, and mechanisms of toxicity, Toxicologic Pathology, 29(1), 41-8, 2001
Sellers RS, Schuller DE, Sharma PK, Tannehill-Gregg SH, Capen CC, Rosol TJ, Head and neck squamous cell carcinoma: measurement of plasma parathyroid hormone-related protein and serum and urine calcium concentrations, Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-head and Neck Surgery., 123(5), 558-62, November 2000
Rosol TJ, Pathogenesis of bone metastases: role of tumor-related proteins, Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research., 15(5), 844-50, May 2000
Kunakornsawat S, Rosol TJ, Capen CC, Reddy GS, Binderup L, Inpanbutr N, Effects of 1,25-dihydroxyvitamin D3 and its analogues (EB1089 and Analog V) on canine adenocarcinoma (CAC-8) in nude mice, . In, Vitamin D Endocrine System Structural, Biological, Genetic, and Clinical Aspects (eds. Norman AW, Bouillon R, Thomasset M), University of California, Riverside, pp. 537-540, 2000
Rosol TJ, Capen CC, Cancer-Associated Hypercalcemia, In, SchalmÃ‚Â’s Veterinary Hematology, Fifth Edition, (eds. BF Feldman, JG Zinkl, NC Jain), Lippincott Williams & Wilkins, Philadelphia, pp. 660-666, 2000
Rosol TJ, Chew DJ, Nagode LA, Schenck P, Disorders of calcium. Hypercalcemia and hypocalcemia, In, Fluid Therapy in Small Animal Practice, (ed. SP DiBartola), WB Saunders Co., Philadelphia, pp. 108-162, 2000
Dougherty KM, Blomme EA, Koh AJ, Henderson JE, Pienta KJ, Rosol TJ, McCauley LK, Parathyroid hormone-related protein as a growth regulator of prostate carcinoma, Cancer Research, 59(23), 6015-22, December 1999
Koh AJ, Beecher CA, Rosol TJ, McCauley LK, 3'',5''-Cyclic adenosine monophosphate activation in osteoblastic cells: effects on parathyroid hormone-1 receptors and osteoblastic differentiation in vitro., Endocrinology, 140(7), 3154-62, July 1999
Blomme EA, Sugimoto Y, Lin YC, Capen CC, Rosol TJ, Parathyroid hormone-related protein is a positive regulator of keratinocyte growth factor expression by normal dermal fibroblasts., Molecular and Cellular Endocrinology, 152(1-2), 189-97, 25 Jun 1999
Blomme EA, Dougherty KM, Pienta KJ, Capen CC, Rosol TJ, McCauley LK, Skeletal metastasis of prostate adenocarcinoma in rats: morphometric analysis and role of parathyroid hormone-related protein., Prostate, 39(3), 187-97, 15 May 1999
Wojcik SF, Capen CC, Rosol TJ, Expression of PTHrP and the PTH/PTHrP receptor in purified alveolar epithelial cells, myoepithelial cells, and stromal fibroblasts derived from the lactating rat mammary gland., Experimental Cell Research, 248(2), 415-22, 1 May 1999
Blomme EA, Zhou H, Kartsogiannis V, Capen CC, Rosol TJ, Spatial and temporal expression of parathyroid hormone-related protein during wound healing., Journal of Investigative Dermatology, 112(5), 788-95, May 1999
Okada H, Miyake Y, Ohtsuka H, Kiku Y, Fukuda S, Watanabe A, Yokomizo Y, Rosol TJ, Yoshino T, Effects of isoprothiolane on cell growth of cultured bovine mammary epithelial cells, The Journal of Veterinary Medical Science / the Japanese Society of Veterinary Science., 61(5), 553-6, May 1999
Rosol TJ, Mammalian calcium metabolism, In, Calcium Metabolism: Comparative Endocrinology, (eds. J Danks, C Dacke, G Flik, C Gay), BioScientifica Ltd., Bristol, pp. 119-130, 1999
Rosol TJ, Stromberg PC, Taylor JL, Fisher SW, Estenik JF, Parathyroid gland hyperplasia in female snapping turtles (Chelydra serpentina) during egg-laying, In, Calcium Metabolism: Comparative Endocrinology, (eds. J Danks, C Dacke, G Flik, C Gay), BioScientifica Ltd., Bristol, pp. 113-116, 1999
Rosol TJ, Taylor JL, Fischbach DG, Matkovic V, Eberts MD, Huff SN, Morgan KM., Effects of daily administration of human parathyroid hormone (1-34) of salmon calcitonin in green iguanas (Iguana iguana), In, Calcium Metabolism: Comparative Endocrinology, (eds. J Danks, C Dacke, G Flik, C Gay), BioScientifica Ltd., Bristol, pp. 75-80, 1999
Capen CC, Rosol TJ, The Calcium Regulating Hormones: Parathyroid Hormone, Calcitonin, and Cholecalciferol, In, Veterinary Endocrinology and Reproduction, 5th edition, chapter 4, (ed. Pineda MH), Lea & Febiger, 1999
Okada H, Ohtsuka H, Kon Nai S, Kirisawa R, Yokomizo Y, Yoshino T, Rosol TJ, Effects of lipopolysaccharide on production of interleukin-1 and interleukin-6 by bovine mammary epithelial cells in vitro, The Journal of Veterinary Medical Science / the Japanese Society of Veterinary Science., 61(1), 33-5, Jan 1999
Grone A, Weckmann MT, Blomme EA, Capen CC, Rosol TJ, Dependence of humoral hypercalcemia of malignancy on parathyroid hormone-related protein expression in the canine anal sac apocrine gland adenocarcinoma $CAC-8$ nude mouse model., Veterinary Pathology, 35(5), 344-51, September 1998
Doss J C, Grone A, Capen C C, Rosol T J, Immunohistochemical localization of chromogranin A in endocrine tissues and endocrine tumors of dogs., Veterinary Pathology, 35(4), 312-5, July 1998
Blomme E A, Sugimoto Y, McCauley L K, Lin Y C, Capen C C, Rosol T J, Stromal and epithelial cells of the canine prostate express parathyroid hormone-related protein, but not the PTH/PTHrP receptor., Prostate, 36(2), 110-20, 1 Jul 1998
Blomme E A, Werkmeister J R, Zhou H, Kartsogiannis V, Capen C C, Rosol T J, Parathyroid hormone-related protein expression and secretion in a skin organotypic culture system., Endocrine, 8(2), 143-51, April 1998
Wojcik SF, Schanbacher FL, McCauley LK, Zhou H, Kartsogiannis V, Capen CC, Rosol TJ, Cloning of bovine parathyroid hormone-related protein $PTHrP$ cDNA and expression of PTHrP mRNA in the bovine mammary gland., Journal of Molecular Endocrinology, 20(2), 271-80, 1998
Blomme E A, Weckmann M T, Capen C C, Rosol T J, Influence of extracellular matrix macromolecules on normal human keratinocyte phenotype and parathyroid hormone-related protein secretion and expression in vitro., Experimental Cell Research, 238(1), 204-15, 10 Jan 1998
Gröne A, Weckmann MT, Capen CC, Rosol TJ, Regulation of Parathyroid Hormone-Related Protein Expression in a Canine Squamous Carcinoma Cell Line by Colchicine, Toxicologic and Experimental Pathology, 50, 365-370, 1998
Werkmeister JR, Blomme E, Weckmann MT, Gröne A, McCauley LK, Wade AB, O'Rourke J, Capen CC, Rosol TJ, Effects of transforming growth factor-b1 on parathyroid hormone-related protein expression by normal human keratinocytes, Endocrine, 8, 291-299, 1998
McCauley L K, Koh A J, Beecher C A, Rosol T J, Proto-oncogene c-fos is transcriptionally regulated by parathyroid hormone (PTH) and PTH-related protein in a cyclic adenosine monophosphate-dependent manner in osteoblastic cells., Endocrinology, 138(12), 5427-33, December 1997
Okada H, Ito T, Ohtsuka H, Kirisawa R, Iwai H, Yamashita K, Yoshino T, Rosol T J, Detection of interleukin-1 and interleukin-6 on cryopreserved bovine mammary epithelial cells in vitro., Journal of Veterinary Medical Science, 59(7), 503-7, July 1997
Okada H, Nishijima Y, Yoshino T, Grone A, Capen C C, Rosol T J, Immunohistochemical localization of parathyroid hormone-related protein in canine mammary tumors., Veterinary Pathology, 34(4), 356-9, July 1997
Weckmann M T, Grone A, Capen C C, Rosol T J, Regulation of parathyroid hormone-related protein secretion and mRNA expression in normal human keratinocytes and a squamous carcinoma cell line., Experimental Cell Research, 232(1), 79-89, 10 Apr 1997
Grone A, McCauley L K, Capen C C, Rosol T J, Parathyroid hormone/parathyroid hormone-related protein receptor expression in nude mice with a transplantable canine apocrine adenocarcinoma (CAC-8) and humoral hypercalcaemia of malignancy., Journal of Endocrinology, 153(1), 123-9, April 1997
Gröne A, Rosol TJ, McCauley LK, Blomme E, Wojcik S, Capen CC., Cancer-Associated Hypercalcemia: Parathyroid Hormone-Related Protein (PTHRP) Expression in Low and High Serum Calcium Variants of the Canine Apocrine Adenocarcinoma (CAC-8) Model of Humoral Hypercalce, In, Vitamin D: Chemistry, Biology and Clinical Applications (eds. Norman AW, Bouillon R, and Thomasset M), printed by University of California, Riverside, pp. 497-498, 1997
Rosol TJ, Capen CC., Calcium-regulating hormones and diseases of abnormal mineral (calcium, phosphorus, magnesium) metabolism, Clinical Biochemistry of Domestic Animals, pp., fifth edition, Kaneko JJ (editor), Academic Press, New York, pp. 619-702, 1997
Sharkey L C, Rosol T J, Grone A, Ward H, Steinmeyer C, Production of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor by carcinomas in a dog and a cat with paraneoplastic leukocytosis [see comments], Journal of Veterinary Internal Medicine, 10(6), 405-8, November 1996
Grone A, Weckmann M T, Steinmeyer C L, Capen C C, Rosol T J, Altered parathyroid hormone-related protein secretion and mRNA expression in squamous carcinoma cells in vitro., European Journal of Endocrinology, 135(4), 498-505, October 1996
Okada H, Schanbacher F L, McCauley L K, Weckmann M T, Capen C C, Rosol T J, In vitro model of parathyroid hormone-related protein secretion from mammary cells isolated from lactating cows., Domestic Animal Endocrinology, 13(5), 399-410, September 1996
Rosol T J, Capen C C, Pathophysiology of calcium, phosphorus, and magnesium metabolism in animals., Veterinary Clinics of North america. Small Animal Practice, 26(5), 1155-84, September 1996
McCauley L K, Koh A J, Beecher C A, Cui Y, Rosol T J, Franceschi R T, PTH/PTHrP receptor is temporally regulated during osteoblast differentiation and is associated with collagen synthesis., Journal of Cellular Biochemistry, 61(4), 638-47, 15 Jun 1996
Grone A, Weckmann M T, Capen C C, Rosol T J, Canine glyceraldehyde-3-phosphate dehydrogenase complementary DNA: polymerase chain reaction amplification, cloning, partial sequence analysis, and use as loading control in ribonuclease protection as, American Journal of Veterinary Research, 57(3), 254-7, March 1996
Rosol TJ, Capen CC, Current Update on the Regulation and Metabolism of Calcium, Phosphorus and Magnesium, Veterinary Clinics of North America, Clinical Pathology Update Issue, Raskin R (editor), Saunders, Philadelphia, 26, 1155-1184, 1996
Rosol TJ, McCauley LK, Steinmeyer CL, Capen CC, Nucleotide sequence of canine preproparathyroid hormone, In: The Comparative Endocrinology of Calcium Regulation. Ed by C Dacke, J Danks, I Caple, and G Flik. Bristol, Journal of Endocrinology Ltd., Bristol, pp. 201-203, 1996
Rosol TJ, Nagode LA, Chew DJ, Steinmeyer CL, Capen CC, Current status of the pathogenesis of humoral hypercalcemia of malignancy in dogs, In: The Comparative Endocrinology of Calcium Regulation. Ed by C Dacke, J Danks, I Caple, et al. Bristol, Journal of Endocrinology Ltd., Bristol, 1996
Rosol T J, Steinmeyer C L, McCauley L K, Grone A, DeWille J W, Capen C C, Sequences of the cDNAs encoding canine parathyroid hormone-related protein and parathyroid hormone., Gene, 160(2), 241-3, 28 Jul 1995
Okada H, Capen C C, Rosol T J, Immunohistochemical demonstration of parathyroid hormone-related protein in thyroid gland of sheep., Veterinary Pathology, 32(3), 315-7, May 1995
Tabuenca A, Mohan S, Garberoglio CA, Borgen PI, Rosol T, Linkhart TA, Parathyroid hormone-related protein: primary osteolytic factor produced by breast tumor cells in vitro?, World Journal of Surgery, 19(2), 292-7; discussion 29, 1995
Okada H, Merryman J I, Capen C C, Rosol T J, Ultrastructural and histomorphometric evaluations of gallium nitrate on bone in nude mice bearing a canine adenocarcinoma (CAC-8) model of humoral hypercalcemia of malignancy., Veterinary Pathology, 32(1), 36-42, January 1995
Rosol TJ, Chew DJ, Nagode LA, Capen CC, Pathophysiology of calcium metabolism, Veterinary Clinical Pathology, 24, 49-63, 1995
Capen CC, Gröne A, Bucci TJ, Rosol TJ, Age-related changes in structure and function of the mouse parathyroid gland, Pathobiology of the Aging Mouse, U Mohr, DL Dungworth, CC Capen, J Sundberg (editors), International Life Sciences Institute Press, 1995
Chew DJ, Nagode LA, Rosol TJ, Carothers MA, and Schenck, Utility of Diagnostic Assays in the Evaluation of Hypercalcemia and Hypocalcemia: PTH, Vitamin D Metabolites, PTHrP, and Ionized Calcium, Current Veterinary Therapy 12, pp. 378-383, J.D. Bonagura (editor), W.B. Saunders Co., Philadelphia, 1995
Rosol T J, Nagode L A, Robertson J T, Leeth B D, Steinmeyer C L, Allen C M, Humoral hypercalcemia of malignancy associated with ameloblastoma in a horse., Journal of The American Veterinary Medical Association, 204(12), 1930-3, 15 Jun 1994
Merryman J I, DeWille J W, Werkmeister J R, Capen C C, Rosol T J, Effects of transforming growth factor-beta on parathyroid hormone-related protein production and ribonucleic acid expression by a squamous carcinoma cell line in vitro., Endocrinology, 134(6), 2424-30, June 1994
Merryman J I, Capen C C, Rosol T J, Effects of gallium nitrate in nude mice bearing a canine adenocarcinoma (CAC-8) model of humoral hypercalcemia of malignancy., Journal of Bone and Mineral Research, 9(5), 725-32, May 1994
Okada H, Merryman J I, Rosol T J, Capen C C, Effects of humoral hypercalcemia of malignancy and gallium nitrate on thyroid C cells in nude mice: immunohistochemical and ultrastructural investigations., Veterinary Pathology, 31(3), 349-57, May 1994
Grone A, Werkmeister J R, Steinmeyer C L, Capen C C, Rosol T J, Parathyroid hormone-related protein in normal and neoplastic canine tissues: immunohistochemical localization and biochemical extraction., Veterinary Pathology, 31(3), 308-15, May 1994
McCauley L K, Beecher C A, Melton M E, Werkmeister J R, Juppner H, Abou-Samra A B, Segre G V, Rosol T J, Transforming growth factor-beta1 regulates steady-state PTH/PTHrP receptor mRNA levels and PTHrP binding in ROS 17/2.8 osteosarcoma cells., Molecular and Cellular Endocrinology, 101(1-2), 331-6, May 1994
Matias-Guiu X, Prat J, Young R H, Capen C C, Rosol T J, Delellis R A, Scully R E, Human parathyroid hormone-related protein in ovarian small cell carcinoma. An immunohistochemical study., Cancer, 73(7), 1878-81, 1 Apr 1994
Rosol TJ, Chew DJ, Hammer AS, Ward H, Peterson JL, Carothers MA, Couto CG, Effect of mithramycin on hypercalcemia in dogs, Journal of the American Animal Hospital Association, 30, 244-250, 1994
Okada H, Merryman JI, Rosol TJ, Capen CC, Effects of humoral hypercalcemia of malignancy and gallium nitrate on thyroid C-cells in nude mice: Immunohistochemical and ultrastructural investigations, Veterinary Pathology, 31(3), 349-357, 1994
Rosol TJ, Gröne A, Werkmeister JR, Weckmann MT, Capen CC, Production of parathyroid hormone-related protein by normal and neoplastic keratinocytes, Journal of Bone and Mineral Metabolism, 12, S161-164, 1994
Capen CC, Okada H, Merryman JI, Rosol TJ, Effects of gallium nitrate in nude mice bearing a canine adenocarcinoma model of humoral hypercalcemia of malignancy: Biochemical, histomorphometric, and ultrastructural investigations, Journal of Bone and Mineral Metabolism, 12, S165-168, 1994
Okada H, Schanbacher FL, McCauley LK, Capen CC, Weckmann MT, Rosol TJ, Secretion of parathyroid hormone-related protein by bovine mammary cells in vitro, Journal of Bone and Mineral Metabolism, 12, S157-160, 1994
Rosol TJ, Nagode LA, Couto CG, Hammer AS, Chew DJ, Steinmeyer CL, Capen CC., Serum 1,25-dihydroxyvitamin D levels in dogs with cancer-associated hypercalcemia and elevated levels of parathyroid hormone-related protein, In 'Vitamin D a Pluripotent Steroid Hormone: Structural Studies, Molecular Endocrinology and Clinical Applications' (A. W. Norman, R. Bouillon, M. Thomasset, eds.), Walter de Gruyer & Co., Berlin, pp. 498-499, 1994
Kukreja S C, Rosol T J, D'Anza J J, Wimbiscus S A, Effect of transforming growth factor alpha, parathyroid hormone-related protein, or their combination on bone histomorphometry., Bone and Mineral, 23(2), 105-11, November 1993
Nohutcu R M, McCauley L K, Horton J E, Capen C C, Rosol T J, Effects of hormones and cytokines on stimulation of adenylate cyclase and intracellular calcium concentration in human and canine periodontal-ligament fibroblasts., Archives of Oral Biology, 38(10), 871-9, October 1993
Au J L, Wientjes M G, Rosol T J, Koolemans-Beynen A, Goebel E A, Schuller D E, Histocultures of patient head and neck tumors for pharmacodynamics studies., Pharmaceutical Research, 10(10), 1493-9, October 1993
Merryman J I, Capen C C, McCauley L K, Werkmeister J R, Suter M M, Rosol T J, Regulation of parathyroid hormone-related protein production by a squamous carcinoma cell line in vitro., Laboratory Investigation, 69(3), 347-54, September 1993
Werkmeister J R, Merryman J I, McCauley L K, Horton J E, Capen C C, Rosol T J, Parathyroid hormone-related protein production by normal human keratinocytes in vitro., Experimental Cell Research, 208(1), 68-74, September 1993
Reiswig J D, Threlfall W R, Rosol T J, A comparison of endometrial biopsy, culture and cytology during oestrus and dioestrus in the horse., Equine Veterinary Journal, 25(3), 240-1, May 1993
Capen C C, Rosol T J, Pathobiology of parathyroid hormone and parathyroid hormone-related protein: introduction and evolving concepts., Monographs In Pathology, 1-33, 1993
Rosol T J, Steinmeyer C L, McCauley L K, Merryman J I, Werkmeister J R, Grone A, Weckmann M T, Swayne D E, Capen C C, Studies on chicken polyclonal anti-peptide antibodies specific for parathyroid hormone-related protein (1-36)., Veterinary Immunology and Immunopathology, 35(3-4), 321-37, January 1993
Capen CC, Rosol TJ, Pathobiology of Parathyroid Hormone and Parathyroid Hormone-Related Protein: Introduction and Evolving Concepts, Pathology of the Thyroid and Parathyroid Gland, pp. 1-33, V.D. LiVolsi, R.A. DeLellis (editors), Williams and Wilkins, Baltimore, 1993
Capen CC, Rosol TJ, Hormonal Control of Mineral Metabolism, Mechanisms of Surgical Diseases of Small Animals, pp. 841-857, second edition, Bojrab (editor), Lea and Febiger, Philadelphia, 1993
Rosol T J, Capen C C, Mechanisms of cancer-induced hypercalcemia., Laboratory Investigation, 67(6), 680-702, December 1992
McCauley L K, Rosol T J, Capen C C, Effects of cyclosporin A on rat osteoblasts (ROS 17/2.8 cells) in vitro., Calcified Tissue International, 51(4), 291-7, October 1992
Podell M, DiBartola S P, Rosol T J, Polycystic kidney disease and renal lymphoma in a cat., Journal of The American Veterinary Medical Association, 201(6), 906-9, 15 Sep 1992
Rosol T J, Nagode L A, Couto C G, Hammer A S, Chew D J, Peterson J L, Ayl R D, Steinmeyer C L, Capen C C, Parathyroid hormone (PTH)-related protein, PTH, and 1,25-dihydroxyvitamin D in dogs with cancer-associated hypercalcemia., Endocrinology, 131(3), 1157-64, September 1992
Grone A, Rosol T J, Baumgartner W, Capen C C, Effects of humoral hypercalcemia of malignancy on the parathyroid gland in nude mice., Veterinary Pathology, 29(4), 343-50, July 1992
Dimski D S, Buffington C A, Johnson S E, Sherding R G, Rosol T J, Serum lipoprotein concentrations and hepatic lesions in obese cats undergoing weight loss., American Journal of Veterinary Research, 53(7), 1259-62, July 1992
Rosol T J, Chew D J, Couto C G, Ayl R D, Nagode L A, Capen C C, Effects of mithramycin on calcium metabolism and bone in dogs., Veterinary Pathology, 29(3), 223-9, May 1992
Stromberg P C, Rosol T J, Grants I S, Mezza L E, Transplantation of large granular lymphocyte leukemia in congenitally athymic rats., Veterinary Pathology, 29(3), 216-22, May 1992
Schmittgen T D, Koolemans-Beynen A, Webb T E, Rosol T J, Au J L, Effects of 5-fluorouracil, leucovorin, and glucarate in rat colon-tumor explants., Cancer Chemotherapy and Pharmacology, 30(1), 25-30, 1992
McCauley L K, Rosol T J, Merryman J I, Capen C C, Parathyroid hormone-related protein binding to human T-cell lymphotropic virus type I-infected lymphocytes., Endocrinology, 130(1), 300-6, January 1992
Ngan P, Kleeman B, Jordan F, Rosol T, Shanfeld J, Davidovitch, Effect of intermittent pressure on periodontal ligament cell-mediated bone resorption in vitro, In Biologic Mechanisms of Tooth Movement and Craniofacial Adaption, Davidovitch, Z. (ed), EBSCO Media, Birmingham, AL, 1992
Rosol T J, Merryman J I, Nohutcu R M, McCauley L K, Capen C C, Effects of transforming growth factor-alpha on parathyroid hormone- and parathyroid hormone-related protein-mediated bone resorption and adenylate cyclase stimulation in vitro., Domestic Animal Endocrinology, 8(4), 499-507, October 1991
McCauley L K, Rosol T J, Stromberg P C, Capen C C, Effects of interleukin-1 alpha and cyclosporin A in vivo and in vitro on bone and lymphoid tissues in mice., Toxicologic Pathology, 19(1), 1-10, 1991
Shevrin D H, Gorny K I, Rosol T J, Kukreja S C, Effect of etidronate disodium on the development of bone lesions in an animal model of bone metastasis using the human prostate cancer cell line PC-3., Prostate, 19(2), 149-54, 1991
Saito S, Ngan P, Rosol T, Saito M, Shimizu H, Shinjo N, Shanfeld J, Davidovitch Z, Involvement of PGE synthesis in the effect of intermittent pressure and interleukin-1 beta on bone resorption., Journal of Dental Research, 70(1), 27-33, January 1991
Rosol TJ, Merryman JI, McCauley LK, Werkmeister JR, Gröne A, Steinmeyer C, Swayne D, Capen CC, Pathogenesis of cancer-associated hypercalcemia: Characterization of polyclonal antibodies to parathyroid hormone-related protein, In 'Vitamin D 1991 Molecular, Cellular, and Clinical Endocrinology' (A. W. Norman, K. Schaefer, H.G. Grigoleit, D. v. Herrath, eds.), Walter de Gruyer & Co., West Berlin, 1991
Rosol TJ, Capen CC, Merryman JI, Meuten DJ, Hypercalcemia of Malignancy, Model No 260, Supplemental Update, 1991, In Handbook: Animal Models of Human Disease. Fascicle 12. Edited by C.C. Capen, D.B. Hackel, T.C. Jones and G. Migaki. Registry of Comparative Pathology, Armed Forces Institute of Pathology, Washington, DC, 1991
Barengolts E I, Gajardo H F, Rosol T J, D'Anza J J, Pena M, Botsis J, Kukreja S C, Effects of progesterone on postovariectomy bone loss in aged rats., Journal of Bone and Mineral Research, 5(11), 1143-7, November 1990
Rosol T J, Stromberg P C, Effects of large granular lymphocyte leukemia on bone in F344 rats., Veterinary Pathology, 27(6), 391-6, November 1990
Saito S, Rosol T J, Saito M, Ngan P W, Shanfeld J, Davidovitch Z, Bone-resorbing activity and prostaglandin E produced by human periodontal ligament cells in vitro., Journal of Bone and Mineral Research, 5(10), 1013-8, October 1990
Kukreja S C, Rosol T J, Wimbiscus S A, Shevrin D H, Grill V, Barengolts E I, Martin T J, Tumor resection and antibodies to parathyroid hormone-related protein cause similar changes on bone histomorphometry in hypercalcemia of cancer., Endocrinology, 127(1), 305-10, July 1990
Threlfall W R, Carleton C L, Robertson J, Rosol T, Gabel A, Recurrent torsion of the spermatic cord and scrotal testis in a stallion., Journal of The American Veterinary Medical Association, 196(10), 1641-3, 15 May 1990
Rosol T J, Capen C C, Danks J A, Suva L J, Steinmeyer C L, Hayman J, Ebeling P R, Martin T J, Identification of parathyroid hormone-related protein in canine apocrine adenocarcinoma of the anal sac., Veterinary Pathology, 27(2), 89-95, March 1990
Eaton KA, Rosol TJ, Caval syndrome in a Dirofilaria immitis-infected dog treated with dichlorvos, Journal of the American Veterinary Medical Association, 195(2), 223-4, July 1989
Merryman J I, Rosol T J, Brooks C L, Capen C C, Separation of parathyroid hormone-like activity from transforming growth factor-alpha and -beta in the canine adenocarcinoma (CAC-8) model of humoral hypercalcemia of malignancy., Endocrinology, 124(5), 2456-63, May 1989
McCauley L K, Rosol T J, Capen C C, Horton J E, Shanfeld J, Investigations on in vitro bone resorbing activity from athymic (nude) and euthymic mouse splenic leukocytes., Bone, 10(5), 389-94, 1989
Lopate C, Threlfall WR, Rosol TJ, Histopathologic and gross effects of testicular biopsy in the dog, Theriogenology, 32, 585-602, 1989
Capen CC, Rosol TJ, Calcium-regulating hormones and diseases of abnormal mineral (calcium, phosphorus, magnesium) metabolism, Clinical Biochemistry of Domestic Animals, pp. 682-756, fourth edition, Kaneko JJ (editor), Academic Press, New York, 1989
Rosol TJ, Capen CC, Tumors of the parathyroid gland and circulating parathyroid hormone-related protein associated with persistent hypercalcemia, Toxicologic Pathology, 17(2), 346-56, 1989
Capen CC, Rosol TJ, Recent advances in the structure and function of the parathyroid gland in animals and the effects of xenobiotics, Toxicologic Pathology, 17(2), 333-45, 1989
McCauley LK, Rosol TJ, Capen CC, Horton JE, A comparison of bone turnover in athymic (nude) and euthymic mice: biochemical, histomorphometric, bone ash and in vitro studies, Bone, 10(1), 29-34, 1989
Rosol TJ, Capen CC, Horst RL, Effects of infusion of human parathyroid hormone-related protein-(1-40) in nude mice: histomorphometric and biochemical investigations, Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research., 3(6), 699-706, December 1988
Kukreja SC, Rosol TJ, Shevrin DH, York PA, Quantitative bone histomorphometry in nude mice bearing a human squamous cell lung cancer, Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research., 3(3), 341-6, June 1988
Rosol TJ, Capen CC, Inhibition of in vitro bone resorption by a parathyroid hormone receptor antagonist in the canine adenocarcinoma model of humoral hypercalcemia of malignancy, Endocrinology, 122(5), 2098-102, May 1988
Frazer GS, Rosol TJ, Threlfall WR, Weisbrode SE, Histopathologic effects of dimethyl sulfoxide on the horse endometrium, American Journal of Veterinary Research, 49, 1774-1781, 1988
Frazer GS, Rosol TJ, Threlfall WR, Effect of serial intrauterine dimethyl sulfoxide infusions on the incidence of periglandular fibrosis in category II horse endometria, Theriogenology, 29, 1091-1098, 1988
Rosol TJ, Chew DJ, Capen CC, Sherding RG., Acute hypocalcemia associated with infarction of parathyroid gland adenomas in two dogs, Journal of the American Veterinary Medical Association, 192, 212-214, 1988
Rosol TJ, Capen CC, Deftos LJ, Horst RL, Nude mouse model (CAC-8) of humoral hypercalcemia of malignancy with increased serum levels of 1,25-dihydroxycholecalciferol, . In 'Vitamin D 1988 Molecular, Cellular, and Clinical Endocrinology' (A. W. Norman, K. Schaefer, H.G. Grigoleit, D. v. Herrath, eds.), Walter de Gruyer & Co., West Berlin, p 867, 1988
Rosol TJ, Capen CC, Pathogenesis of humoral hypercalcemia of malignancy, Domestic Animal Endocrinology, 5(1), 1-21, January 1988
Rosol TJ, Chew DJ, Capen CC, Sherding RG, Acute hypocalcemia associated with infarction of parathyroid gland adenomas in two dogs, Journal of the American Veterinary Medical Association, 192(2), 212-4, January 1988
Rosol TJ, Capen CC, The effect of low calcium diet, mithramycin, and dichlorodimethylene bisphosphonate on humoral hypercalcemia of malignancy in nude mice transplanted with the canine adenocarcinoma tumor li, Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research., 2(5), 395-405, October 1987
Rosol TJ, Capen CC, Brooks CL, Bone and kidney adenylate cyclase-stimulating activity produced by a hypercalcemic canine adenocarcinoma line (CAC-8) maintained in nude mice, Cancer Research, 47(3), 690-5, February 1987
Nishikawa S, Rosol TJ, Capen CC, Effects of mithramycin on transplantable canine perianal gland carcinoma (CAC-9) in nude mice: biochemical, histomorphometric, and ultrastructural investigations, Veterinary Pathology, 23(6), 698-705, November 1986
Rosol TJ, Capen CC, Minkin C, In vitro bone resorption activity produced by a hypercalcemic adenocarcinoma tumor line (CAC-8) in nude mice, Calcified Tissue International, 39(5), 334-41, November 1986
Andrews FM, Rosol TJ, Kohn CW, Reed SM, DiBartola SP, Bilateral renal hypoplasia in four young horses, Journal of the American Veterinary Medical Association, 189(2), 209-12, July 1986
Rosol TJ, Capen CC, Weisbrode SE, Horst RL, Humoral hypercalcemia of malignancy in nude mouse model of a canine adenocarcinoma derived from apocrine glands of the anal sac. Biochemical, histomorphometric, and ultrastructural studies, Laboratory Investigation; a Journal of Technical Methods and Pathology, 54(6), 679-88, June 1986

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